雖然與亞運撞期，但美網會外賽女單還是有14位亞洲選手參賽，
中國最多，佔7人；其次是日本5人；
新傭兵選手Rybakina首次代表哈薩克參賽。
分布在八區，其中有兩場首輪是亞洲選手碰頭。
(1)鄭賽賽 v Jil Teichmann
Myrtille Georges v 日比万葉
Lesley Kerkhove v 蔣蘇貞
Victoria Duval v (31)Sofya Zhuk
(5)Vitalia Diatchenko v Karolina Muchova
逯佳境 v Jasmine Paolini
Francoise Abanda v Jessika Ponchet
Olivia Rogowska v (22)Beatriz Haddad Maia
(7)Arantxa Rus v Irina Khromacheva
Irina Falconi v Elena Rybakina
Nina Stojanovic v Aliona Bolsova Zadoinov
Cagla Buyukakcay v (27)劉方舟
(11)Heather Watson v (wc)Cori Gauff
清水綾乃 v 韓馨蘊
Katie Swan v Deborah Chiesa
土居美咲 v (17)日比野菜緒
(12)朱琳 v Anna Zaja
Danka Kovinic v Jessica Pier!
Fanny Stollar v Barbora Krejcikova
Jaqueline Cristian v (24)Vera Zvonareva
(14)Magdalena Frech v Danielle Lao
Amandine Hesse v Conny Perrin
Lauren Davis v Lina Gjorcheska
張宇璇 v (19)Jana Fett
(15)Mariana Duque-Marino v Anna Rodionova
(wc)Jessica Pegula v (wc)Kayla Day
Patty Schnyder v Maryna Zanevska
魯晶晶 v (20)Veronika Kudermetova
(16)Eugenie Bouchard v Carol Zhao
(wc)Catherine McNally v Ekaterine Gorgodze
波形純理 v Jamie Loeb
Bibiane Schoofs v (18)Ysaline Bonaventure