單打96簽的邁阿密大賽，各種子均首輪輪空。亞洲球員列種子的有女單的第二種子
大坂直美、21種子Rybakina、26種子Putintseva。男單則有28種子錦織圭、32種子
Bublik。
首輪男女單共有女四男三獲得晉級。
[女單]
DIYAS, Zarina def. WILLIAMS, Venus 6-2 7-6
王薔 def. BOLSOVA, Aliona 6-1 3-6 6-3
WC-王欣瑜 def. PETERSON, Rebecca 6-2 6-2
鄭賽賽 def. FERRO, Fiona 2-6 6-4 6-3
OSTAPENKO, Jelena def. WC-王曦雨 6-4 6-7 6-1
ZARAZUA, Renata def. 日比野菜緒 6-4 4-6 6-1
MARTINCOVA, Tereza def. SHVEDOVA, Yaroslava 6-4 6-2
PETKOVIC, Andrea def. 張帥 7-5 6-1
[男單]
盧彥勳 def. QUERREY, Sam 6-3 6-4
內山靖崇 def. CARUSO, Salvatore 6-3 6-4
KUKUSHKIN, Mikhail def. DRAPER, Jack 7-5 0-0 Ret'd
NORRIE, Cameron def. 西岡良仁 6-1 3-6 7-5
Q-KOKKINAKIS, Thanasi def. Q-望月慎太郎 MOCHIZUKI, Shintaro 6-3 6-3
IVASHKA, Ilya def. 權純雨 7-6 6-7 7-6