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~ 50 ORNs -> Antennal lobe -> 50 Glomerulus -> ~50 PNs -> MB & LH
50 ORNs 一對一連接 50 PNs 在不同的glomeruli
形成至少50個平行傳輸通道
ORN由一到兩個ORGs表達，以及在glomerulus中axon匯聚 而定義
=>
ORN怎麼定義?
1. 看哪個ORGs表達
2. 看axon在哪個glomerulus中converge
PNs也是要看drite在哪個glomerulus
~60 ORNs & ~3 PNs在單一個glomerulus中形成幾百組synapses
重點: every ORN forms synapses with every PN to
convey the same type of plfactory information
PNs that project to the same glomerulus have indistinguishable
electrophysiological properties and olf responses.
=> seems like same glomerulus's PNs have same electrophysiological properties
and olf responses
=> Use single-cell RNASeq to establish the relationship between
1. Transcriptome
2. Neuronal cell identity
3. Development
Drosophila pupal, not in adult.
PN marker => GH146-GAL4
Astrocyte marker => alrm-GAL4