大家可以用
Gemcitabine after Folfirinox 去找已經做過的實驗
杏國的藥是SB05PC + Gemcitabine 跟 Gemcitabine 單藥比.
以我任取一篇的結論來看
https://reurl.cc/Qd05GZ
Folfirinox失敗後用Gemcitabine繼續治療
96 patients were included (male, 51%; median age, 62;
performance status (PS) 0-1, 47%).
Median duration on gemcitabine was 2.1 months.
The overall disease control rate was 40%.
Median OS was 3.7 months (95%CI: 2.5-5.2) and
median PFS was 2.1 months (95%CI: 2.0-2.6)
96個病患,平均年紀62歲,
mOS 3.7個月
mPFS 2.1個月
大家可以去找杏國二期實驗收進的病人狀況(幾歲,多少人等)
mOS是 7.3個月, 比上面的實驗多了3.6個月
數學好的應該可以根據這些數據稍微算一下期中分析成功的機率,
期末分析成功的機率各是多少?
當然杏國的賣點是將紫衫醇包進去的技術,若胰臟癌成功還可以推廣到其他癌症,
所以第一個適應症最重要,也希望他成功啦!