課程名稱︰訊息傳遞與疾病
課程性質︰選修
課程教師︰主授陳青周（此範圍為陳青周/李建國/蔡丰喬老師授課）
開課學院：醫學院
開課系所︰醫衛共同課程
考試日期（年月日）︰2017/06/09
考試時限（分鐘）：110分鐘
試題 :
(以下敘述均非與原題目完全相同，僅就考試主題作最接近之題目描述)
陳青周老師part：佔45分
(範圍：NF-κB and Ubiquitination; Epigenetic mechanisms;
Targeting transduction pathways for research and medical intervention)
問答題：
1. Please describe two examples of epigenetic drugs. Detail their functions
and the mechanisms. (10%)
2. What is bivalent histone methylation? (5%)
3. Describe the process of ubiquitination: use IκBα as example. (15%)
4. Targeting growth factor signaling pathway, choose one example of monoclonal
antibody drug and one example of small drug and detail their modes of
actions. (15%)